Amphetamine

$375.00$9,600.00

IUPAC ID: 1-phenylpropan-2-amine

Drug class: CNS stimulant, anorectic

Duration of action: IR dosing: 3–6 hours; XR dosing: 8–12 hours

Onset of action: IR dosing: 30–60 minutes; XR dosing: 1.5–2 hours

Other names: α-methylphenethylamine

Metabolism: CYP2D6, DBH, FMO3

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Description

Amphetamine

Amphetamine is used to treat attention deficit hyperactivity disorder (ADHD), narcolepsy (a sleep disorder), and obesity, and is sometimes prescribed off-label for its past medical indications, particularly for depression and chronic pain. Long-term amphetamine exposure at sufficiently high doses in some animal species is known to produce abnormal dopamine system development or nerve damage, but, in humans with ADHD, pharmaceutical amphetamines, at therapeutic dosages, appear to improve brain development and nerve growth. Reviews of magnetic resonance imaging (MRI) studies suggest that long-term treatment with amphetamine decreases abnormalities in brain structure and function found in subjects with ADHD, and improves function in several parts of the brain, such as the right caudate nucleus of the basal ganglia.
Adverse Effects
Cardiovascular side effects can include hypertension or hypotension from a vasovagal response, Raynaud’s phenomenon (reduced blood flow to the hands and feet), and tachycardia (increased heart rate). Sexual side effects in males may include erectile dysfunction, frequent erections, or prolonged erections. Gastrointestinal side effects may include abdominal pain, constipation, diarrhea, and nausea. Other potential physical side effects include appetite loss, blurred vision, dry mouth, excessive grinding of the teeth, nosebleed, profuse sweating, rhinitis medicamentosa (drug-induced nasal congestion), reduced seizure threshold, tics (a type of movement disorder), and weight loss. Dangerous physical side effects are rare at typical pharmaceutical doses.
Amphetamine.

Effects of amphetamines

There is no safe level of drug use. Use of any drug always carries some risk. It’s important to be careful when taking any type of drug.

Amphetamines affect everyone differently, based on:

  • size, weight and health
  • whether the person is used to taking it
  • whether other drugs are taken around the same time
  • the amount taken
  • the strength of the drug (varies from batch to batch with illegally produced drugs).

You might feel the effects of amphetamines immediately (if injected or smoked) or within 30 minutes (if snorted or swallowed).You might experience:

  • happiness and confidence
  • talking more and feeling energetic
  • large pupils and dry mouth
  • fast heartbeat and breathing
  • teeth grinding
  • reduced appetite
  • increased sex drive.6-8

Research has found an association between amphetamine use and increased violent behaviour.9

Snorting amphetamines can damage the nasal passage and cause nose bleeds.

If injecting drugs, there is an increased risk of:

  • tetanus
  • infection
  • vein damage and blood clots.10, 11

If sharing needles, there is an increased risk of:

  • hepatitis B.
  • hepatitis C.
  • HIV and AIDS.12

Giving up amphetamines after a long time is challenging because the body has to get used to functioning without them.Withdrawal symptoms should settle down after a week and will mostly disappear after a month. Symptoms include:

  • cravings for amphetamines
  • increased appetite
  • confusion and irritability
  • aches and pains
  • exhaustion
  • restless sleep, vivid dreams and nightmares
  • anxiety, depression and paranoia

Additional information

Quantity

1000g, 100g, 10g, 250g, 500g, 50g

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