Formula: C18H27NO
ChemSpider ID: 9952762
PubChem CID: 11778080
Molar mass: 273.420 g·mol−1
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3-MeO-PCP is a derivative of PCP and is a dissociative. 3-MeO-PCP stands for 3-Methoxyphencyclidine. This chemical falls into the aryl cyclohexylamine class. It was first synthesized in the year 1979. Experiments with 3-MeO-PCP typically yield results that are similar to those of other dissociatives like PCP or MXE. However, researchers have described the results of 3-MeO-PCP to be more stimulating and less immobilizing than the results of those other chemicals. Other findings that are commonly associated with 3-MeO-PCP include anxiety suppression, disinhibition, cognitive euphoria, conceptual thinking, creativity enhancement, and time distortion.
Those of us experienced with dissociatives will remember the less potent chemical 4-MEO-PCP – but 3-MEO-PCP is a major improvement. Even when testing measurements as low as 4mg, interesting reactions are produced in the lab.
Always store in a cool, dry place for maximum shelf-life. This product is intended for forensic and research applications only. It is therefore NOT intended for human consumption or in-vivo testing of any kind on animals or any living organism.

We present in this case report a validated method for accurate quantitative analysis of 3-methoxy phencyclidine (3-MeO-PCP) to determine postmortem blood concentrations of this PCP analog. A 29-year-old male with a history of illicit drug use was found unresponsive in his bed with a bag of white powder next to him. Resuscitation efforts were unsuccessful and the individual was pronounced dead 9 minutes after arrival to the hospital. Initial ELISA screening suggested the presence of PCP in the decedent’s blood. However, confirmatory testing revealed no detectable PCP. Instead, a large peak corresponding to a m/z 274.218 species with retention time similar to PCP was present on a LC-TOF-MS drug screen, suggesting a possible PCP analog. This mass corresponds specifically to a methoxy-PCP analog, several of which are available for purchase online. Standards for 3-MeO-PCP and 4-MeO-PCP were obtained and injected on the same instrument. Although the 3- and 4-MeO-PCP analogs have identical masses and retention times, they are still distinguishable through their mass spectra. The peak from the decedent’s sample matched both the mass spectrum and the retention time of 3-MeO-PCP. A quantitative LC–MS-MS method was subsequently developed and validated for casework. Analysis using this method revealed a concentration of 139 ± 41 µg/L 3-MeO-PCP in the decedent’s blood. Diphenhydramine (4.1 ± 0.7 mg/L), marijuana metabolite (presumptive positive, confirmation not performed) and a small amount of amphetamine (<0.10 mg/L) were also found in the decedent’s blood. The cause of death was determined to be combined 3-MeO-PCP, diphenhydramine and amphetamine toxicity. The manner of death was certified as an accident.

A potent dissociative often compared to MXE but with a longer duration, much less sedating effects and causing an overall different experience. Users have reported effects as being similar to PCP. Roughtly ten times more potent than 4-MeO-PCP.

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1000g, 100g, 10g, 250g, 500g, 50g


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