3-Hydroxyphencyclidine (3-HO-PCP)


IUPAC Name: 3-(1-(piperidin-1-yl)cyclohexyl)phenol

Molecular Formula: C17H25NO

Molecular Mass: 259.39g/mol

CAS NO: 79295-51-5

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3-HO-PCP stands for 3-Hydroxyphencyclidine. It is a dissociative chemical that falls into the arylcyclohexylamine class. It is an NMDA receptor antagonist. 3-HO-PCP was first synthesized in 1978. It has been a favorite for research chemists for many years.
3-HO-PCP experiments typically yield findings of stimulation, sedation, physical euphoria, tactile enhancement, pain relief, changes in gravity perception, disinhibition, conceptual thinking, time distortion, increased music appreciation, thought connectivity, hallucinations, and perspective distortion. It is very potent so make sure that you follow all laboratory safety procedures if you experiment with it. 3-HO-PCP is a great addition to any lab.
Where to buy 3-HO-PCP?
3-HO-PCP can be purchase from Fire Brand Chemicals. We offer high-quality 3-HO-PCP for sale, typically in powder form. However, if you would like a different form, then feel free to contact us to let us know because we often have different forms available.
You must be at least 18 years old to buy 3-HO-PCP from us and be in full legal compliance with the research chemical laws of your country.
NOTE; The 3-HO-PCP is not intended for human or animal consumption. It is only intended for research purposes.

1-(1-(3-hydroxyphenyl)-cyclohexyl)piperidine, PCP-3-OH, Phenol, 3-(1-(1-piperidinyl)cyclohexyl)-


3-Hydroxyphencyclidine (3-HO-PCP) is a new psychoactive substance (NPS) and a hydroxy derivative of phencyclidine (PCP), and N-ethylhexedrone (Hexen) is a synthetic cathinone. We describe an analytically confirmed case of acute toxicity related to the use of both 3-hydroxyphencyclidine and N-ethylhexedrone.

Case Report

A 56-year-old male was brought to the Emergency Department by ambulance with hyperthermia (39.9 °C), sinus tachycardia (150 beats per minute), reduced consciousness, ocular clonus, and vertical nystagmus. He was treated with cooled intravenous (IV) fluids and IV benzodiazepines. Following 1 hour of treatment, his temperature fell to 37.7 °C, he developed rhabdomyolysis (creatine kinase peaked at 5999 IU (normal range < 229 IU)): he was managed with supportive measures and was discharged after 25 hours. The patient admitted regular use of Hexen and recent use of 3-HO-PCP. Analysis of urine and serum identified 3-hydroxyphencyclidine and metabolites, N-ethylhexedrone and metabolites, and clephedrone and metabolites.


This is a case of analytically confirmed toxicity to 3-HO-PCP and N-ethylhexedrone. The acute toxicity reported in this patient is consistent with the use of 3-HO-PCP, but there were sympathomimetic and serotonergic features potentially consistent with the cathinone N-ethylhexedrone. The description of the acute toxicity of NPS, such as these, is vital to aid medical toxicologists and emergency medicine physicians treating patients who use them.

Keywords: 3-Hydroxyphencyclidine, N-Ethylhexedrone, NPS (novel psychoactive substance) toxicity, Cathinone, PCP

Additional information


1000g, 100g, 10g, 250g, 500g, 50g


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