3′,4′-Methylenedioxy-α-pyrrolidinobutiophenone ( mdphp-201)
$200.00 – $2,050.00
Formal Name: 1-(1,3-benzodioxol-5-yl)-2-(1-pyrrolidinyl)-1-butanone, monohydrochloride
CAS Number: 24622-60-4
Molecular Formula: C15H19NO3 • HCl
Formula Weight: 297.8
Formulation1: A crystalline solid
3′,4′-Methylenedioxy-α-pyrrolidinobutyrophenone (MDPHP) is a stimulant of the cathinone class developed in the 1960s, which has been reported as a novel designer drug. MDPHP is sometimes sold under the name “NRG-1” as a mixture with other cathinone derivatives, including flephedrone, pentylone, MαPPP, and its higher homolog MDPV. As with other cathinones, MDPBP has been shown to have reinforcing effects in rats.
The main metabolic steps are thought to be demethylenation followed by methylation of one hydroxy group, aromatic and side-chain hydroxylation, oxidation of the pyrrolidine ring to the corresponding lactam as well as ring-opening to the corresponding carboxylic acid. CYP2C19 and CYP2D6 have been identified as the isoenzymes mainly responsible for demethylenation.
Butyrophenones are chemical compounds with a ketone functional group that have anti-
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